Knight Dermatology Institute

Dermatology and Mohs located in Winter Park, Melbourne, FL, Orlando, & Lake Mary, FL

    1. "My questions are always answered with great patience and I feel very well taken care of."

    2. Elizabeth S. Google

    1. "Very good doctor and staff. Nice office."

    2. William G. Google

    1. "The staff are great and very professional and very knowledgeable."

    2. Eddie W. Google

    1. "Always timely and thorough!"

    2. Christian S. Google

Knight Dermatology Institute is a comprehensive medical facility run by fellowship trained and board-certified practitioners.  Our goals are simple:  to cure skin cancer and help our patients feel wonderful about their skin and appearance. 

Schedule Your Appointment Today

Download Patient Forms Here

Meet Dr. Knight

A nationally recognized speaker and author, J. Matthew Knight, M.D. is a board certified dermatologist specializing in skin cancer, laser surgery, and cosmetic dermatology.

Learn More



Weird sleep habits that can affect your health

Can you really get beauty sleep? Sleep habits can affect your skin health....


Sunscreen at school

Sunscreen use can cut kids’ risk of melanoma by 50% – so why is it so hard to bring it to school in Florida?...


What your skin says about you health

What our skin can tell us about our overall health and how it can warn us about serious medical problems....


Protecting Yourself From Summer Sun

Protecting Yourself From Summer Sun

What your skin says about your health...

What your skin says about your health...

Our Locations

Choose your preferred location


Words from our patients

  • "Dr. Knight has been my Dr. for 20 years. His office and staff are wonderful!"

    Debbie S.
  • "The care I receive there is excellent. They listen, provide options and help you determine the course of treatment that works for you."

    Joseph Z.
  • "I would highly recommend Knight Dermatology to friends and family. I called on Thursday and they got me in the next day which was great."

    Leah B.
  • "HIGHLY RECOMMEND THIS PRACTICE! I was taken in at the time of my appointment and looked after immediately, paying less than originally anticipated as well."

    Bashir I.

Most Major Insurance Plans Accepted

Knight Dermatology Institute participates in most major health insurance plans including Medicare, Blue Cross Blue Shield, Cigna, Aetna, Health Choice, TRICARE and United Health Care. However, please verify at the time that your appointment is made that we participate with your particular insurance plan.

Advent Health Plans
Blue Cross Blue Shield
Bright Health
First Health
Medicare Part B
Meritain Health
Multiplan PPO
United Health Care
United Healthcare AARP

photo of Knight Dermatology Institute

photo of Knight Dermatology Institute

photo of Knight Dermatology Institute

photo of Knight Dermatology Institute

photo of Knight Dermatology Institute


Fax Number Fax Number by Locations

Knight Dermatology Institute

Orlando, FL

Fax: 407-992-7702

Knight Dermatology Institute

Lake Mary, FL

Fax: 407-915-7226

Knight Dermatology Institute

Winter Park, FL

Fax: 321-203-4226

Knight Dermatology Institute

Melbourne, FL

Fax: 407-992-7702