Knight Dermatology Institute

Dermatology and Mohs located in Orlando & Lake Mary, FL

    1. "My questions are always answered with great patience and I feel very well taken care of."

    2. Elizabeth S. Google

    1. "Very good doctor and staff. Nice office."

    2. William G. Google

    1. "The staff are great and very professional and very knowledgeable."

    2. Eddie W. Google

    1. "Always timely and thorough!"

    2. Christian S. Google


Knight Dermatology Institute is a comprehensive medical facility run by fellowship trained and board-certified parctitioners.  Our goals are simple:  to cure skin cancer and help our patients feel wonderful about their skin and appearance. 

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Meet Dr. Knight

A nationally recognized speaker and author, J. Matthew Knight, M.D. is a board certified dermatologist specializing in skin cancer, laser surgery, and cosmetic dermatology.

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Office Locations
  • Orlando Location:


    801 N. Orange Ave., Suite 520
    Orlando, Florida 32801
    Phone: 407-992-0660
    Fax: 407-992-7702


    Get Directions

    Parking Instructions

    Lake Mary Location:


    1035 Primera Blvd. Suite 1041
    Lake Mary, FL, 32746
    Phone: 407-992-0660
    Fax: 407-915-7226


    Get Directions

Our Locations

Choose your preferred location


Words from our patients

  • "Dr. Knight has been my Dr. for 20 years. His office and staff are wonderful!"

    Debbie S.
  • "The care I receive there is excellent. They listen, provide options and help you determine the course of treatment that works for you."

    Joseph Z.
  • "I would highly recommend Knight Dermatology to friends and family. I called on Thursday and they got me in the next day which was great."

    Leah B.
  • "HIGHLY RECOMMEND THIS PRACTICE! I was taken in at the time of my appointment and looked after immediately, paying less than originally anticipated as well."

    Bashir I.

Most Major Insurance Plans Accepted

Knight Dermatology Institute participates in most major health insurance plans including Medicare, Blue Cross Blue Shield, Cigna, Aetna, Health Choice, TRICARE and United Health Care. However, please verify at the time that your appointment is made that we participate with your particular insurance plan.

Advent Health Plans
Blue Cross Blue Shield
Bright Health
First Health
Meritain Health
Multiplan PPO
United Health Care
United Healthcare AARP