KNIGHT
DERMATOLOGY
Board-certified dermatologists in Central Florida specializing in advanced skin cancer treatment, Mohs surgery, and comprehensive medical dermatology.
Four Central Florida locations
Board-Certified Dermatologists
Knight Dermatology specializes in the early detection, precise diagnosis, and advanced treatment of skin cancer, providing compassionate care with the latest technology to ensure the best outcomes. Proudly delivering expert, patient-centered skin care across Orlando, Lake Mary, Winter Park, and Melbourne, FL.
Book Appointment
Knight Dermatology offers comprehensive medical and cosmetic dermatology care, from skin cancer screenings to advanced aesthetic treatments.
Schedule your visit today and get personalized care from our experienced dermatology team.
Skin Cancer Care, From Prevention to Reconstruction
Central Florida’s strong year-round sun makes skin cancer one of the most common concerns we see. Skin cancer care is the foundation of Knight Dermatology: Dr. J. Matthew Knight is a board-certified Mohs surgeon, Chief of Dermatology for Orlando Health, and the founder and first director of the Orlando Health UF Health Melanoma & Skin Cancer Center. From your first skin check to your final follow-up, your care stays with one experienced team.
Step 01
Prevention & Skin Checks
Daily sun protection and regular full-body skin exams are the best defense against skin cancer. We check moles and spots from head to toe and help you build a sun-safe routine for Florida living.
Step 02
Accurate Diagnosis
Our board-certified dermatologists closely examine new or changing spots and perform in-office biopsies when needed, so skin cancer is found early, when it is most treatable.
Step 03
Mohs Surgery & Treatment
Mohs micrographic surgery removes skin cancer layer by layer and examines 100% of the margin while you wait. It offers the highest cure rate for basal and squamous cell carcinoma while preserving healthy skin.
Step 04
Reconstruction & Recovery
When skin cancer is removed from the face or other visible areas, our fellowship-trained Mohs surgeons and double board-certified plastic surgeon, Dr. George Pope, repair the area with both function and appearance in mind.
Dr. J. Matthew Knight
Board-certified dermatologist widely recognized for his expertise in skin health and skin cancer treatment.
In addition to leading Knight Dermatology in Florida, he frequently appears on television as a trusted medical expert, offering clear, accessible advice on dermatology and general health topics.











